Wednesday, February 29, 2012

Report: UCLA players undermined discipline, morale (AP)

[unable to retrieve full-text content]AP - Players and staff members from the past four UCLA basketball teams say that coach Ben Howland allowed an influx of talented but immature recruits to undermine team discipline and morale as the once-proud program has struggled to live up to its storied history, Sports Illustrated reported Wednesday.

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20120229/ap_on_sp_co_ne/bkc_ucla_disarray

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NH unemployment 5.2 percent, unchanged in January (AP)

[unable to retrieve full-text content]AP - The New Hampshire Department of Employment Security says the state's unemployment rate in January was 5.2 percent, the same as December.

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/ap/20120228/ap_on_bi_ge/us_january_unemployment_new_hampshire

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Tuesday, February 28, 2012

We're eating out less, opting for chains more

Andrew Gombert / EPA

Chain restaurants are faring better than indepdendents lately.

By Allison Linn

Think of the last time you went out to eat, and be honest: Did you chow down at a favorite locally owned haunt, or opt for the familiarity of a chain restaurant?

A new report from market researchers NPD Group finds that overall, Americans are eating out less than? few years ago, as the weak economy has caused people to cut back on such splurges. Total restaurant visits have fallen every year since 2008, from 62.7 billion restaurant visits that year to 60.6 billion in 2011.

The cutbacks have hit mom-and-pop restaurants much harder than chains. The NPD Group data shows that independent restaurants now account for 27 percent of restaurant visits, down from 28 percent in 2008.

When business falls, closures are inevitable. Although the number of independent restaurants increased slightly between 2008 and 2009, many independent restaurateurs have since had to throw in the towel.

In the past two years, NPD reports that the number of independent restaurants in the U.S. has fallen by 8,652. In that same two-year period, the number of chain restaurants has increased by 1,750.

Do you tend to eat out at chain or indepdendent restaurants?

Source: http://lifeinc.today.msnbc.msn.com/_news/2012/02/27/10519020-were-eating-out-less-and-opting-for-chains-more

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Energy Efficiency Enhancing Home Improvement Projects ...

Tips for Choosing the Right Blogs for Guest Posting

When most people talk about a particular internet business method there is usually a certain amount of existing knowledge that is taken for granted. For example, if you are reading a tutorial on loan, then some amount of knowledge on that subject will be assumed to exist.

There are certain advertising and marketing methods that so many have the wrong idea about due to people spreading rumors and false information on the net.

This is just part of the nature of online business or even offline for that matter. When you think about it, those who allow themselves to become stagnant in business are the ones who get left behind. So it would be a good idea to discover more on your own before you launch a complete campaign.

Guest blogging can be a remarkable method to receive more very targeted exposure for your blog without to invest money on it. As a guest blogger, you have the opportunity to create posts and have them published on numerous blogs within your niche market and receive lots more traffic for yourself. Unfortunately, you can?t merely publish on any old blog?you should choose exactly the appropriate blog for the submission of the posts. Unless you may be able to take care of the, you aren?t going to find the kinds of results that you need to see. In this article we will talk about three incredibly worthwhile elements that you can employ to narrow down the options of blogs to publish your guest posts.

Make intelligent employ of Google when you?re shopping for blogs to guest post on. Search engines, and specifically Google, are not just worthwhile for general searches but also for acquiring blogs in your niche. You?ll be able to look according to several factors, to bring up the most relevant blogs. You may also want to look under your keywords along with the phrase ?guest posts? and see what comes up. Stick to standard blogs that are up-to-date frequently, as the others aren?t value the trouble.

A important element that you should consider when you may be choosing a blog for guest posting is how relevant it happens to be. If the blog is not relevant then obviously you aren?t going to receive a entire lot from it, even if you do receive published.

You like to make certain that that your post is published on a blog or webpage with the appropriate kind of audience. Reach out to additional people that might be interested in your website or what you have to provide. It?s true that you can earn backlinks even from publishing on irrelevant blogs but it?s merely not value the effort. There is no question, by those with experience and success, that Safe can accomplish a lot for your business. We know of people who have been doing business on the web for many years, yet they have not used all the methods that are out there; so it just depends on your situation. If you have had your business for just a few months, you may not know all you need to know especially if your time is very limited. We always strive to offer very helpful information that is actionable; it is by no means a thorough presentation. There are evergreen areas of marketing and advertising that are specific to the internet, but innovation is always a possibility that you should explore whenever the spirit strikes you.

Internal linking is a important thing, make certain that that the blog you choose has a strong system in place. The reasoning here isn?t that complicated: blogs without internal linking show a lack of SEO knowledge. Selecting a blog with this in place, however, does tell you that the owner of the blog believes in sending traffic to old posts and also new ones. One of the goals must be guaranteeing that your guest posts are getting good degrees of traffic both internally and externally. This is merely 1 of the factors a blog must have a wise internal linking structure.

Most internet marketers are familiar with guest blogging, though not everybody benefits from it because much because they might. In order to benefit because much because possible from guest blogging, you need to begin with the appropriate blog. Using the strategies that we discussed in the above mentioned article, you are able to see that you can find a blog that?s value it. Focusing your efforts in the appropriate method enables you to enjoy the extended term benefits of guest blogging. Submitting your posts to the appropriate blogs is the initial step in gaining the extended range benefits of guest blogging.

If you are fairly unfamiliar with the techniques covered in this article, then that is all right and really no problem at all. Each particular strategy involving Ideal that you read about has much more to learn because there are finer details about different scenarios, for example. Not everything you read will be directly applicable to your business, but it is still a great thing to learn new stuff just because you never know.

New online marketers can sometimes get lost in the process of discovery and spend a bit too much time buried in books.

The obvious issue and danger here is your mind can fool you by having the feeling you are getting work done when you are not. Being in business means you are engaged in the process, and the process is whatever is dictated by your particular business model.

Tags: Home, loan home improvement, projects

This entry was posted on Monday, February 27th, 2012 at 1:24 pm and is filed under Uncategorized. You can follow any comments to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.

Source: http://shelljamguitardesign.com/energy-efficiency-enhancing-home-improvement-projects

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Monday, February 27, 2012

Mazda3 discount targets Ford Focus

image for 'Mazda3 discount targets Ford Focus'

The Ford Focus has long been considered the best small family hatchback on the road today - as mentioned yesterday in our report on the new Chevrolet Cruze.

However, over the years if there has been one car which can genuinely claim to challenge the Ford Focus in terms of on-road handling, responsiveness and driving fun it is the Mazda3 hatchback.

Mazda uses the term 'zoom zoom' to describe its philosophy and lightweight, agile models such as the Mazda MX-5 sports car highlight where its priorities are.

A new 2011 Ford Focus left the old Mazda3 a little behind, not just in terms of styling but in the case of equipment and even performance on the road.

But this could all change with a new, revamped 2012 Mazda3 complete with revised styling a more premium interior and plenty of extra equipment.

The new Mazda3 is more aerodynamic than before and boasts some good diesel engines, including the most powerful available in the small hatchback segment, the 2.3-litre diesel.

This should get people's attention and for a short time only, new Mazda3 prices will start from ?13,495 - ?500 lower than entry-level Ford Focus prices.

The extra ?500 is good, but even more impressive is the fact the new Mazda3 price of ?13,495 is for a 1.6-litre TS model. This is not an entry-level model, instead it is a mid-range specification with air conditioning, climate control and a radio/CD player as standard.

Compared to the Ford Focus Studio, the entry-level mode, this represents more equipment at a lower price and while the low Mazda3 prices are temporary, it could give the Mazda3 the edge in the lucrative 12-plate market when the new registration plates are introduced in March.

When you compare Ford Focus prices with those of the new Mazda3 (which starts from ?14,995 without the discount) the Blue Oval model remains the pick of the two.

However, for a short period the Mazda3 not only undercuts the Ford Focus prices, but it offers more equipment as well.

As the March plates near, the new 2012 Mazda3 is well worth a look as an affordable and fun-to-drive alternative to the Ford Focus.

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Source: http://www.oneswoop.com/research/articles/news/mazda3-discount-targets-ford-focus-6727.aspx

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Sunday, February 26, 2012

Pets: Ways to Choose Care of the Canine ...

February 25, 2012 by Guest Poster

The Bond which can arrive between a person plus a dog snuggie might be exceptionally robust, especially if that bond had been strengthened dwelling with one another for quite some time, We have personally cried right after loosing our family members pet that had been like a very best friend to me from my birth till I as fifteen a long time previous, when he was hit by an automobile one morning.

Puppies serve lots of distinctive wants for folks. Lots of people have a dog simply because they are lonely and need a loyal companion or simply because they want a puppy to guard the house. A pet dog that is definitely taken fantastic care of and given attention to frequently will give his existence that will help guard his home and his owner. For the blind a puppy might be a pair of eyes to help them get close to and for that police a puppy could be a very important resource and a loyal partner, by using a nose that absolutely nothing can beat.

The first point you should know about taking care of a canine is the fact that pet dogs want tons of dog snuggie work out. This can be the exact for substantial canines and small dogs. All puppies should be let out at the least once each 8 hrs and really should supplied no less than a twenty minute stroll to give the dog some fresh air, exercising along with a opportunity to alleviate themselves.

Additionally it is vital that you engage in with all the canine often. This will imply really going to your park on the weekend or day off and having a good recreation of fetch, tossing the ball all-around as part of your again property or simply wrestling about the floor while using pet dog, just be certain when you are ruff housing using a little canine which you don?t unintentionally harm the dog. Enjoying along with the pet to get a half hour on a daily basis, is simply not only good to the dogs physical wellness but a dig that may be performed with frequently is mentally more healthy and a smaller amount likely to become a frustrated pet, additionally, it lowers your blood pressure level also and it will form an unbreakable bond among both you and your pooch, which will prolong on your family members when you need to start out owning one immediately after obtaining the pet.

Whatever you feed your pet may be very important to the pet dogs ongoing excellent wellness. The higher dog snuggie will likely be marked for exactly what are groups the foods is suitable for. Youthful canines want specific vitamins and minerals in even larger quantities then an grownup pet, along with the same goes for an elderly pet dog they require additional calcium within their foodstuff to aid safeguard their bones and joints. Feeding your puppy the wrong meals can stunt the dog?s progress and opens the dog to a even larger threat of surgical procedures once they are older.

Just like anyone a dog must be taken to the veterinarian?s business office every 6 months, and should acquire their pictures yearly. Common checkups and vaccinations may even help assure that your dog grows to generally be an aged content puppy.


Source: http://windowslosangelescounty.com/pets-ways-to-choose-care-of-the-canine/

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Rick Santorum, in Michigan, presents vision for his first 100 days in office (Washington Post)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/204452738?client_source=feed&format=rss

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Saturday, February 25, 2012

Easy Ideas For Easier Living With Arthritis | New Health and Fitness

New Health And Fitness.Org - Health Information You Can Use

A recent study indicated that many people believe that only older adults can suffer from the painful condition known as arthritis. On the contrary, this disease can affect adult men and women as well as children. If you are struggling with arthritis, the information in this article will offer insight into the condition.

If you have arthritis, try reducing your caffeine intake. Some people are extremely sensitive to arthritis. In those individuals, reducing the consumption of caffeine can have a positive effect on arthritis symptoms. Reduce the amount of caffeine you consume gradually to best gauge if your results will be positive ones.

For arthritis sufferers with severe range of motion issues as well as those with fingers severely affected with inflamed joints, finding and putting on supportive footwear can be a challenge. Look for shoes with Velcro closures for ease, and while backless, slip-on shoes like clogs might be tempting, make sure they are low to the ground and have a wide, stable foot bed to prevent injuries from falling.

Stretch your legs and get moving stretching your legs is a simple way to keep muscles flexible. Stretching will help you to relieve your stress and will help you maintain your daily activities. Try to keep your muscles strong and flexible. Do some simple, stretching exercise, daily will help you to be more mobile and flexible.

Whenever you dwell on something, you just make it worse. It is important in your healing process not to dwell on the bad things but instead dwell on the good things. Remember things that are important to you that you want to focus on, and take your mind off of the pain.

Occupational therapy has been known to help people who suffer from arthritis. Sometimes this kind of therapy is covered by many health insurance plans. Occupational therapy will help identify problem areas in your lifestyle and work with you to find ways to eliminate them or help you work with them to lead a more pain free life.

If you suffer from the pain of arthritis flare ups, try to remember to keep your pain relievers handy. Many pain relievers like ibuprofen can help relieve symptoms of arthritis flare ups in as little as 15 minutes. So make sure to keep a bottle of your most effective pain reliever close at hand.

Most exercise programs for people who suffer from the pain and stiffness of arthritis include range-of-motion exercises. Range-of-motion is the normal amount of distance that your joints can move in a certain direction. These types of exercises help to keep your joints flexible. Some physicians also recommend Tai Chi as an alternative to improve flexibility and increase muscle strength.

Studies have shown that calcium and magnesium supplements help to alleviate arthritis pain and other pain of the body. These minerals are recommended to be taken as a preventative more than as a painkiller. It has also been proven to help women reduce pain associated with premenstrual syndrome if taken consistently.

In many cases, becoming more knowledgeable about a condition makes it much easier to seek out treatment options that are best for each individual. By following the advice that you have just read, you will be better prepared to make the necessary adjustments to continue living with arthritis free from pain. We know you want to discover more about Arthritis Remedies, and coming up next is one thing we believe will help you in ways you do not realize, yet. Research is time consuming and hard, but we think we have come across the very best as you will soon discover. But, in fairness, we will tell you that it is easy to make crucial mistakes if you do not have the precise informaton.

To get a grip on pertinent hints about Natural arthritis cures and even on Reactive arthritis treatment, read this incredibly informative site.

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Source: http://newhealthandfitness.org/2012/02/24/easy-ideas-for-easier-living-with-arthritis/

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Hamas sets new terms for reconciliation with Fatah (Reuters)

[unable to retrieve full-text content]Reuters - Hamas has set new terms for implementing a reconciliation deal with Palestinian President Mahmoud Abbas's rival Fatah group, an official said on Thursday, dimming even further chances the accord will be put into effect.

Source: http://us.rd.yahoo.com/dailynews/rss/mideast/*http%3A//news.yahoo.com/s/nm/20120223/wl_nm/us_palestinians_unity

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Friday, February 24, 2012

Thursday, February 23, 2012

Energy Investing in Saskatchewan | Oakshire Financial

Tom MacNeill doesn?t have to go far to find the most unique early-stage energy companies to invest in. The President and CEO of Saskatchewan-based investment firm 49 North Resources, MacNeill is bullish on his own backyard, and says of the province?s resources, ?You name it, we?ve got it.? In this exclusive interview with The Energy Report, he explains why Saskatchewan resource plays trump their Alberta or Ontario counterparts.

The Energy Report: Even some of the most successful small-cap resource investors were schooled in 2011. What did you learn from last year?s ups and downs?

Tom MacNeill: We were definitely reminded of the nature of resource investments. Liquidity absolutely vanished in 2008, but by the time it reappeared in 2009 and 2010, investors had decided they wanted to keep their hands on their cash. Oil entered and exited 2011 at roughly the same price, but at times it had been much higher and much lower. That spooked investors. It became evident that most of the investors who were still comfortable with equity investments preferred dividend paying structures. It?s been a very edgy time.

We were reminded that investors were walking on thin ice. The companies that stepped up and started increasing distributions from their oil and gas production were well served. Those that did not, were not. There?s been a bifurcation in the market. The entire capped energy index is down relative to most of the broader indexes for the simple reason that investors were withdrawing money from the sector even though one barrel (bbl) of oil was about $100 throughout the year.

TER: Will the legacy of 2011 be the split between those companies that brought in dividends and those that didn?t?

TM: It?s one of the legacies. A lot of companies die in the aftermath of an event like the 2008 downturn. However, not enough undeserving companies died off because they had just completed financings and had millions of dollars in their treasuries that enabled them to weather the storm. We didn?t have enough of a rout.

Going into 2011, there were still a bunch of these Johnny-come-latelies and investors got wise. They started to watch the burn rate and what management was doing. It was a wakeup call. It was a really bad year in ?08, it was OK in ?09 and ?10, and then ?11 leveled as investors became objective. I believe that investors are more objective this year than they have been in five years.

TER: Your company doesn?t just invest in resource companies, it also instills management teams and brings in consultants with specific expertise. It?s an investor and a partner.

TM: We?ve had to be a little bit of everything within 49 North. We act as in-house management for developing companies. We provide seed capital and later-stage capital. We?ve got 25-plus of the best geoscientists in Saskatchewan on staff in one of our subsidiary companies, Northrim Exploration Ltd. That enterprise works with most of the senior players working in the province developing potash, oil and gas, and other sedimentary resources and is moving into hard rock mining consultation. We also have substantial connections within the junior resource capital market and investment banking community worldwide.

We had to develop it that way for the simple reason that we had no capital market in Saskatchewan. Where government used to hold business back, it is now very supportive. The resource business is now wide open. It?s a tremendous opportunity for us, and anybody who wants to invest in the province, because it?s like Alberta was in the ?40s and ?50s.

TER: Saskatchewan certainly shares some of the same commodities with Alberta.

TM: We view ourselves as much better off than Alberta from a geological perspective. The Western Canadian Sedimentary Basin overlays almost all of Alberta, meaning there?s really no hard rock mining with the exception of some coal mining and some other assets in the Rockies. Alberta is very much an ?energy only? resource province.

Saskatchewan is the opposite. The sedimentary basin covers the southern half, but the northern half is exposed Precambrian shield. We?ve got all of the mining prospectivity and assets that you would find in Ontario and other hard rock jurisdictions, plus all of the oil and gas that you find in Alberta, and a sea of potash and other natural resources. You name it, we?ve got it. The neatest part is that it?s mostly still in the ground. There are 27 active mines in the province, but we should have a multiple of that given our resource base.

TER: How long do you think it will take you to get to that point?

TM: We have just begun, but it is moving fast. There is $15 billion (B) worth of capital committed already to expansion in the potash industry, not including capital commitments from BHP Billiton Ltd. (BHP:NYSE; BHPLF:OTCPK), which is moving into the final feasibility stage of its 8 million tons (Mt) per annum potash mine at Jansen Lake. When mining is combined with our exponential growth in energy development I expect that $15B will double or triple in the next 5-10 years.

One new gold mine just came on-stream this past year. There are three others that are prospective in the Greenstone Belt in northern Saskatchewan. There?s a potential rare earth elements deposit that?s near development. In the next 10 years, at least 10?20 mining operations should reach feasibility in the province.

TER: One commodity that Saskatchewan is well known for is uranium. The Athabasca Basin is one of the richest areas for uranium in the world. In a 2010 interview with The Gold Report, you told us that you had mostly purged uranium from 49 North Resources? portfolio and wouldn?t get back in until it was ?time.? Is it time yet?

TM: The comments I made were based on a couple of observations. There was a physical price spike in 2006 due to uranium speculators. It created a parabolic price chart, so we knew that the price of uranium was going to come off. When that happens, all of the junior explorers get crucified. We took that time to exit our positions.

We?ve been diligently watching the uranium price chart and energy complex in general and view this year as the time to be taking positions. Uranium stocks have been beaten up. That?s the time when we get involved in projects and we?re actively pursuing more than what we have on the books right now.

We?ve got a significant investment in Unity Energy Corp. (UTY:CVE), which is an early-stage explorer in the same area as Hathor Exploration Ltd.?s (HAT:TSX.V) RoughRider deposit and the area were Fission Energy Corp. (FIS:TSX.V; FSSIF:OTCQX) is exploring. Also we have been accumulating a large position in Eagle Plains Resources. They have substantial landholdings in the Athabasca basin in Saskatchewan and recently announced a high-grade uranium discovery on their property near the Rabbit and Cigar lake mines.

TER: Tell us about Unity.

TM: It?s in the early stages of a promising exploration program having done the geophysical work necessary to advance their package of properties. We hold approximately 12% of Unity. Given that initial results have been very encouraging, we will likely be expanding our exposure shortly.

TER: What?s the earliest that Unity would have a resource estimate?

TM: They are at a very early stage in the exploration cycle so the earliest would likely be at least 2-3 years. Investors need to realize uranium exploration takes time, is expensive and if you want good science you can?t rush the process. This is a long-term investment, as all uranium exploration plays are.

TER: What macroeconomic trends are going to continue to drive energy commodities?

TM: Oil acts a lot like gold in that it?s a good parking lot for rampant money printing in the U.S. One thing that can quell inflation in the short term is a high oil price since it slops up many of the newly printed dollar bills in an asset that is used almost immediatly. This seems counter-intuitive, but it takes time for the inflationary effect of high oil prices to bleed into higher asset prices. So in the short term, it actually helps the money printers because all over the world, oil is traded in U.S. currency, thus distributing the new liquidity worldwide. The U.S. is the only country with this advantage, which creates some ironic economic activity that investors should pay attention to. As long as the U.S. keeps printing money, there?s going to be a high oil price. If the liquidity being added actually creates economic development, there will be rampant inflation. Usually that?s a tap that can?t be turned off, which could lead to much higher oil and gold prices. We view the coming five-year period as very interesting and probably very lucrative for resource investors, especially in gold and energy.

TER: What energy commodities are you most bullish on this year?

TM: We?re focusing on heavy oil and coal (for conversion to crude oil), but our backyard is unique. There are 20?40 billion barrels (Bbbl) of heavy oil in place in west central Saskatchewan. There are also staggering quantities of light oil as well in Saskatchewan, but I?m not as interested in that. Everyone knows about the Bakken shale and other tight light oil plays now being developed using modern multi-staged fracturing but very few follow heavy oil development.

My interest is tied to the recycle ratio, which is the net profit/bbl divided by acquisition and development costs/bbl. The ratio for light oil in Saskatchewan averages somewhere around two, meaning if a company puts $1 million (M) into acquiring and developing an average well, it will get $2M out of it. But heavy oil in Saskatchewan can have a recycle ratio as high as five.

That?s not true of everywhere in the world. We have two heavy oil upgraders in Saskatchewan that have been consistently adding capacity so we?ve got a real blessing here in that we can develop our heavy oil fields and achieve higher netbacks than elsewhere because of that very unique refining capacity in our backyard.

TER: What are some of the companies benefiting from that?

TM: Most of the companies that are developing these heavy oil assets that are in production are very large already and beyond our scope, such as Canadian Natural Resources LTD. (CNQ;TSX) and Baytex Energy Corp. (BTE.UN:TSX). We?re sponsoring private companies in this space. However, Baytex is coming up with ingeneous ways to drill multiple lateral wells from one drill pad and get enormous production out of thin-formation, heavy oil projects. They also pay a pretty decent dividend yield as well. That?s the kind of story we?re looking for, but we?re looking for it at a very early stage when a company has a prospective heavy oil development field and is investing its first $1?5M in the project.

TER: Are any of your private oil plays expected to go public?

TM: Probably. Allstar Energy Ltd., in west central Saskatchewan, is a light oil producer that is converting into a heavy oil producer as well. We?ve actually taken that one in-house and made it a subsidiary company. Had the capital markets been a little bit more buoyant over the last nine months, we might have entertained taking that company public sometime last year. At some point, given it?s growth potential, its capital needs will outstrip our ability to supply it and we?ll have to take the training wheels off and take it public. That could be in 2012 or 2013 depending on how development goes.

We also sponsor Admiralty Oil Ltd., a very early-stage light oil development in southeastern Saskatchewan. It will probably go public if it has some success this year.

TER: You said you are bullish on coal. What are some of your holdings in that space?

TM: There are two that we really like, which are both developing coal-to-liquid technology. We view coal as just another long carbon chain that can be converted into a shorter carbon chain to make heavy crude. These two enterprises are going about it in different ways.

NuCoal, a private company in southern Saskatchewan, will use full gasification to convert coal into transportation fuels at the mine site. It?s a multibillion-dollar project. The company has control of one of the largest coal resources in the world and it could possibly go public sometime in the next 12?18 months.

Westcore Energy Ltd. (WTR:TSX.V), which we have an approximate 25% stake in, has a significant thermal coal resource that it?s developing on the Saskatchewan-Manitoba border. It is working with Quantex Energy in Calgary, which has a proprietary technology developed at the University of West Virginia. Quantex tested some of Westcore?s coal and determined that it?s perfectly adequate for converting into heavy or light crude depending on the extent of processing.

Westcore is currently starting its winter drilling exploration program. It already has at least seven defined targets that have hit intersections as thick as 100 meters (m) of coal, which is absolutely enormous. It?s conservative to estimate that those intersections average 50Mt/coal, which could mean that the company has at least 300Mt/coal in one small area. That?s world class. It appears it will cost about $40-50/bbl of oil for the conversion technology. It will probably cost approximately $200M to build an initial 10,000 bbl/day conversion facility. Given that the process appears to convert coal to heavy crude at a ratio of 3-4 bbl crude from each ton of coal, there?s an almost endless potential supply of heavy crude oil for the refiners in Saskatchewan. Now that is an exciting energy story.

TER: It does sound exciting. Is the process by which they turn coal into heavy oil similar to what?s happening in the oil sands where they steam the bitumen to separate the oil from the sand and gravel?

TM: That?s a liberating technique using steam to get the bitumen. Then the bitumen is processed through hydrocracking, which involves heating up the bitumen under pressure with catalysts to separate it by strata into various elements. The lights float to the top of the column and the heavy stuff stays at the bottom, leaving five or six different strata. These synthetic crude products are then piped to refineries for further processing. The NuCoal project is similar to that in that it uses similar full-scale gasification technology but with the intention of the plant refining all the way to the transportation fuel level right on site.

The Westcore/Quantex route involves using a low-temperature direct liquefaction process. It adds some proprietary chemicals to the coal once it?s emulsified and converts it into heavy crude. The beauty is that the process does not leave much of a greenhouse gas footprint at the mine/processing site because most of the carbon dioxide and other problematic gases that would be emitted stay in the heavy crude and go to the refinery. The exciting part about low temperature conversion is its scale-ability with initial capital cost of probably one tenth that of full-scale gasification.

Both companies have viable approaches; they are simply on opposite ends of the development spectrum. One has low capital cost with smaller initial production while the other has large capital requirements at startup and therefore large initial output. At these energy prices we believe both approaches will be robustly economic.

TER: Once it?s converted it goes to the refineries. Where does the oil go from there?

TM: It is channeled into the North American distribution system running from northern Alberta into a hub center near Chicago. It goes directly into the pipeline system that bisects Saskatchewan diagonally. That?s the beauty. We?re infrastructure laden because we?re in between the consumptive market in the eastern U.S. and the production of western Canadian oil sands and conventional producers in the Western Canadian Sedimentary Basin.

TER: Do you have some parting thoughts on the energy space?

TM: I?m curious to see what prices are going to do. We?re comfortable that the price of uranium has bottomed and that it?s likely a very long-term bottom. We got our feet wet last year in some of the early-stage investments we?ve made. We?re going a lot harder this year and repatriating capital back into projects that we like. There are lots of good opportunities out there within companies that have done poorly in this twitchy market but have good projects.

The energy space should be an exciting one. If the governments keep adding liquidity, the resulting competitive devaluation of currencies will be inflationary and good for commodity prices. Or perhaps the world is going to get a little bit better?also good for commodity prices. It?s a bit of a win-win situation over the next five years if investors are patient.

Investors have to make sure that they stick to certain criteria. Look at management first, not the project, because the best project in the world can be screwed up by bad management. A marginal project can be made wonderful by good management.

TER: Thanks, Tom.

Tom MacNeill is the founder, president and chief executive officer of 49 North Resources Inc., a Canadian resource investment company headquartered in Saskatchewan. As the first entity of its kind in the province?s history, 49 North is a pioneer in what is rapidly becoming one of the world?s most renowned resource jurisdictions. A graduate of the University of Saskatchewan (economics/geology), MacNeill is also a certified general accountant and holds a chartered financial analyst designation. MacNeill?s extensive knowledge of Canadian capital markets has been gained through experience as a management accountant within the mining industry, investment advisor with a major Canadian brokerage firm and chief financial officer of a Canadian trust corporation. He is a well-respected member of the resource industry and part of a worldwide network of exploration professionals and resource developers which enables him to source and structure projects.

?
Brian Slyvester
The Energy Report

Source: http://oakshirefinancial.com/2012/02/22/energy-investing-in-saskatchewan/

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Commercial bridging finance

Commercial bridging finance

Every sort of loan in the financial sector is secured to get a purpose. There are various loans you are able to always choose to satisfy the demands of what you are pursuing. Bridging finance is definitely certainly one of such loans that may be of help when you might have a pressing have to own a home. Let's examine the goals of a real loan and the way far better to secure it.

Why Bridging Finance?

Bridging finance or loan is short term in nature. It's a sort of loan that can help someone to secure a residential property even in the big event the person has limited funds. The loan will also help a business to secure a commercial property or even large equipment if the actual fund isn't available. With the loan, a company can manage the money flow gap involving the purchase of an asset along with the sale of a different one inside firm. The loan is therefore very beneficial not limited to real-estate purchases, but additionally for meeting unexpected business demands. As a possible individual it is achievable to use the loan to purchase a building. You can also utilize it to buy shares and pay other outstanding bills. However, the credit is predominantly found in property purchases.

The Duration

Basically, bridging loans are for temporary purposes. The duration varies in accordance with lenders and also the intention which is why they may be meant for. In some quarters, the loan could be for any amount of days, 2 weeks or more. It could even extend to months as well as years. All of it depends about the stipulations involved and the agreement you'll have with the lender.

The Necessity from the Loans

The bridging loans are extremely necessary for success in real-estate deals. The loans are most useful with regards to managing fees and charges that are associated with the buying and selling of properties. The loans are also very essential for purchasing brand-new properties especially when you not have the necessary funds for one-time purchase. The goal of the loan is always to eliminate financial obstacles you could possibly encounter while wanting to purchase your required property.

Securing the Loan Approval

In order to secure the credit approval, you may need to be entitled to it. In most cases, the lending company has to qualify you for that loan. There's that loan approval process you need to undergo as a way to secure the loan. Oftentimes, you may well be needed to complete a pre-approval loan process as a way to discover the amount the lender may offer you. This is generally commensurate with all the quantity of collateral you have. In most cases, the collateral is determined by the Lender. It could be any significant property you've got including heavy machine, inventory, business equipments or some other things like that. When you have to have scaled through the qualification exercise, you're absolutely clear on getting the loan.

The Repayment and Interest Rates

Live every other loan, a bridging loan demands you spend interest according to the terms and conditions agreed upon. In most cases, the eye rate is very high. This is really because in the potential risks involved along with the shortness with the loan period. Moreover, there's always the repayment period. Some lenders may need that you repay the loan in full if the due date reaches. Others may require you to repay the credit on monthly basis.

In all, you are able to always benefit a great deal from bridging loans. Take time for it to check around to be able to choose a reliable lender.





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Source: http://www.vh-ulm.de/groups/anonym/weblog/e0043/

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Wednesday, February 22, 2012

Greek bailout wards off disaster ? for now (AP)

[unable to retrieve full-text content]

Managing Director of the International Monetary Fund Christine Lagarde, left, speaks with Greek Prime Minister Lucas Papademos during a round table meeting of eurozone finance ministers at the EU Council building in Brussels on Monday, Feb. 20, 2012. Eurozone governments will likely approve on Monday a long-elusive rescue package for Greece, saving it from a potentially calamitous bankruptcy next month, senior officials said. But finance ministers meeting in Brussels will have a few last issues to wrangle over, such as tighter controls over Greece's spending and further cuts to the country's debt load.  (AP Photo/Yves Logghe)AP - A second, euro130 billion ($172 billion) bailout and a deep debt write-off for financially stricken Greece will ward off a financial disaster in Europe.


Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/ap/20120221/ap_on_bi_ge/eu_europe_financial_crisis

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Improve Your Relationship: Know When It is Best Not to Say ...

By Suzanne Phillips, Psy.D., ABPP

Whether you have just begun dating or you are celebrating a Golden Anniversary, most partners are aware that communication is a crucial component in relationship happiness and satisfaction. Most self-help books extol it, and most experts working with couples encourage and facilitate improved communication.

Dr. Marianne Legato, author of Why Men Never Remember and Women Never Forget contends that without effective couple communication, there is no relationship at all.

A crucial but often overlooked communication skill for partners is knowing when it is best not to say anything.

This skill is not about suppression, quiet compliance, the silent treatment, dismissal or neglect. It is a choice that reflects attunement, empathy, regulation of emotions and prioritizing the bond you share.

It is knowing those times when your comment, critique, opinion, question or news not only fails to add value ? it makes matters worse!

While there are always differences among couples relative to their personal histories and dynamics, here are some situations that many face for which the decision not to say anything may be best.

Fueling the Fire

  • A real stumbling block for old and young couples who are arguing is knowing when ?enough is enough.? ?More specifically, recognizing that it is an illusion to think that there is something to gain in ?having the last word.?
  • In almost all cases insisting on one more comment does nothing productive. Usually it escalates the tension and anger and jeopardizes resolution.
  • As Ferguson author of Reptiles in Love?suggests, when partners are in fight/flight mode, logic is gone and no one wins.
  • Stopping is a protective and important step in anger management. It prevents saying the unsayable ? those words we can?t take back. It also prevents the dangerous escalation from verbal to physical aggression.

Breaking the Confidence

  • One of the ingredients in the intimacy of any couple is what they share as confidantes. Feeling safe, partners share dreams, frailties, imperfect body parts, traumatic memories and self-doubts in a way they share with no one else.
  • Regardless of what others are disclosing, which family member is asking, or how much everyone is?enjoying ?partner bashing? ? don?t take the bait.
  • Protecting each other?s confidence is a gift of trust only partners can give to each other.

But I Was Just Trying to Help

  • Despite the fact that every couple self-help book recommends that unless asked, don?t give advice ? most of us err in favor of ?just trying to help.?
  • Actually on close reflection, it is often our own sense of anxiety and helplessness in face of?a partner?s distress that throws us into advice mode.? We have to do something!
  • Listening with eye-to-eye contact and hand-to-hand reach is far more powerful than unsolicited advice.? A partner who feels your support is more empowered to solve his/her problem and will more likely ask for help if needed.

?Getting To Not Know You

? I know just what he/she is going to say!?

  • As much as you think you know your partner ? think again. What makes a relationship interesting and vital is recognizing what you still don?t know about each other.
  • Toward this end one verbal talent you want to drop is the compulsion to finish your partner?s sentence. (trust me) ?Listening instead of speaking puts you in a position to hear what you may or may not expect from your partner. Finishing the other?s sentence changes dialogue into monologue. It often shuts down present and future discussion and precludes more knowing.
  • When partners do this to each other in public ? the audience is sent the message that he/she cannot speak for himself/herself or that you need to be in control ? neither option is desirable.

Disqualifying The Compliment

????Great? That?s ridiculous. You know I hate my hair.?

  • Sometimes a childhood history can take its toll on self-esteem or you can hit a tough time in life when a job or a?health situation saps too much of your confidence. These are times when having a loving and affirming partner can be a powerful source for healing and restoring self.
  • These are the times, however, when you may feel compelled to speak? i.e.?to verbally debate, discount or argue away a partner?s compliment. While these are times when nothing feels right, to verbally undo a compliment is to disqualify something important ? a little bit of light sent in by someone who loves you.
  • Positive emotions have the unique quality of broadening and building both social and psychological resources. Accepting a compliment is a positive exchange for both of you.

Taking Up The Family Fight

  • It is inevitable that partners will complain about their families of origin to each other and will enjoy the support of the other in seeing it their way.
  • What never works, however, is feeling entitled to verbally criticize, belittle or put down your partner?s family.? Yes, you have heard about these people. Yes, you have felt outraged and protective of your partner. But your partner needs you to hear it and contain the feelings more than he/she needs you to keep bringing up how outrageous or unacceptable they may be.
  • As difficult as it may be, it is emotionally more supportive to listen than speak about his/her family?because regardless of whether families are bad or good, most people feel connected with them. Often adult children of dysfunctional families carry considerable shame and self-blame which is exacerbated when someone reminds them about it. Needing to feel different and vital, your partner prefers that you focus more on him/her than the family of origin.
  • Listening is what no one may have done in the childhood ? your partner finally has someone willing to do that ? you.

No News is Good News

As much as it is very valuable for couples to share experiences together, it is?also important?to show?respect for and encouragement of each other?s passions and interests in other people, places and things.

His love of watching sports, her weekly book club, his commitment to teaching, her love of nursing are actually valuable to the relationship as they nurture and support each as individuals.

That said, it is important to think twice about verbally intruding into your partner?s recreation or workspace. If you feel a sense of urgency ? put yourself in your partner?s shoes and re-evaluate your urgent need to speak.

  • Does he really need to hear about the painter?s estimate in the middle of the game?
  • Does she really need a call about your 5th grader?s science project at her book club?
  • He does care about the news of your brother in law ? but not in the middle of his workday.
  • She may not fully appreciate your enthusiasm about discount plane fares if she has to hear about it in the hallway at work.

When partners feel that their time and space?are respected, they usually can?t wait to share and hear what the other has to say!

Sharing the Sounds of Silence

  • Often people remark that the way they know that they are really connected is that they can be together without saying anything.
  • This is the place where no one is speaking but a great deal is being communicated.
  • This is the place where both are safe enough in the relationship that they feel the other without having to verbally hold the tie or check the mood with words.
  • This is the place where partners embrace the silence between them as intimate space.

As valuable as the words are between us ? silence can be the most powerful communication of all.?

?

Suzanne B. Phillips, Psy.D., ABPP is a licensed psychologist. She is Adjunct Professor of Clinical Psychology in the Doctoral Program of Long Island University and on the faculty of the Post-Doctoral Programs of the Derner Institute of Adelphi University. Suzanne Phillips, PsyD and Dianne Kane are the authors of Healing Together: A Couple's Guide to Coping with Trauma and Post-Traumatic Stress. Learn more about their work at couplesaftertrauma.com . Visit Suzanne's Facebook Page HERE.

Like this author?
Catch up on other posts by Suzanne Phillips, Psy.D., ABPP (or subscribe to their feed).



????Last reviewed: 21 Feb 2012

APA Reference
Phillips, S. (2012). Improve Your Relationship: Know When It is Best Not to Say Anything!. Psych Central. Retrieved on February 21, 2012, from http://blogs.psychcentral.com/healing-together/2012/02/improve-your-relationship-know-when-it-is-best-not-to-say-anything/

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Source: http://blogs.psychcentral.com/healing-together/2012/02/improve-your-relationship-know-when-it-is-best-not-to-say-anything/

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Tuesday, February 21, 2012

Another look at the LG Optimus Vu -- with television antenna in tow

LG Optimus VU

The LG Optimus Vu is poised to become the latest oversized smartphone when it makes its debut at Mobile World Congress in a week. And tonight, LG global communications director Ken Hong on Twitter showed a picture of it playing Korean KBS TV, with what appears to be an antenna sticking out of one corner. That's not new for Asian phones. The LG Optimus Z we reviewed back in 2010 sported an antenna as well, though for obvious reasons it doesn't do much for us here in the States. 

Source: @visitken



Source: http://feedproxy.google.com/~r/androidcentral/~3/w4CftdUTClU/story01.htm

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Monday, February 20, 2012

A classic model for ecological stability revised, 40 years later

Monday, February 20, 2012

A famous mathematical formula which shook the world of ecology 40 years ago has been revisited and refined by two University of Chicago researchers in the current issue of Nature.

In 1972, physicist Robert May rankled ecologists by publishing a simple model describing the relationship between diversity and stability in a theoretical ecosystem. Though ecologists had long believed that richer, more diverse environments were inherently more resistant to disruption, May's formula argued that more species in fact creates more instability.

But rich ecosystems exist in nature, such as those found in coral reefs or rain forests. For 40 years, ecologists have attempted to expand May's formula to explain how these highly diverse natural systems persist. For the new paper, University of Chicago researchers Stefano Allesina and Si Tang returned to the original equation, and with small mathematical tweaks, reconciled the disagreement between theory and reality.

Adjusting May's formula to incorporate predator-prey or consumer-resource relationships, where one species profits at the expense of another, allows the model to describe an ecosystem where stability is possible even with an infinite number of species.

"Predator-prey relationships are stabilizing. We can fit much larger ecosystems if there's a backbone of predator-prey interactions, and see a lot of species happily co-existing ever after," said Allesina, PhD, assistant professor of Ecology & Evolution at the University of Chicago. "We kind of solved this one puzzle of how can we see very many species in an ecosystem. But then we open different puzzles."

May's original model, also published by Nature, sought to challenge the ecological belief that diverse ecosystems were more resistant to perturbations such as invasive species or abrupt climate change. With his physics training, May set out to create a model of the relationship between diversity and stability with the fewest possible factors, settling upon a model that used only the number of species and the strength of their interactions with each other.

The surprising result of May's model was that large or complex ecosystems were so unstable that their existence was statistically improbable. While that conclusion did not match what ecologists observe in natural systems such as rain forests, which may contain thousands of species in a single tree, the model challenged the simplistic assumption of more diversity leading to more stability.

"May made the beautiful point that nature must adopt some 'devious strategies' to cope with this fact, because if mathematically there is this impossibility of complexity, how come we then observe it in nature?," Allesina said. "It must be that nature uses some sneaky way to violate this rule."

May's article launched the "diversity-stability debate," as ecologists proposed many such "devious strategies" to explain the persistence of rich ecosystems in nature by adding complex qualifiers to his formula. Instead of following this trend, Allesina and Tang went back to the original model and made a small adjustment. They replaced the random species interactions of May's model with three general types of relationships observed between species in nature.

In the "eat-or-be-eaten" world of a predator-prey relationship, one species (the predator) benefits while another species (the prey) suffers a loss of fitness. A competitive relationship between two species can have a negative effect on both, while a relationship of mutualism produces a positive effect for the two species involved.

When each of these interactions is inputted separately into May's formula, the predicted stability for a given number of species changes from his original calculation using a random distribution of species-species interaction. In the predator-prey condition, the stability of the ecosystem is increased such that a large number of species can be supported. In the competition and mutualism systems, the ecosystem is highly unstable and vulnerable to perturbation.

"What we are showing is that of all the types of interactions you can have, only predator-prey can support an infinite number of species," Allesina said. "If you look in nature, there are very obvious consumer-resource relationships everywhere, and maybe this system assembles so easily because these relationships provide a lot of stability."

But just as the revised version of May's formula brings it in line with one natural observation, more counter-intuitive results are created. Many ecologists believe that strong interactions between species, such as when a predator relies upon only one prey species for food, make an ecosystem more vulnerable. However, the revised formula predicts that weak interactions, not strong interactions, are destabilizing to an ecosystem.

Another discrepancy occurs when the model is applied to a realistic food-web structure, rather than the theoretical, random structure used as a default. When a commonly observed natural structure? such as the "cascade" model where each predator eats prey smaller than themselves?is tested with the model, the resulting system is less stable than that produced by a random structure.

But like May's original formula, these disagreements between model and reality offer new opportunities to explore how nature subverts these predictions and produces diverse, stable ecosystems. Many of the "devious strategies" proposed as additions to the original model can now be tested with the revised formula as a reference point.

"I think this is a good step forward, especially because it resuscitates this result that has been so fundamental for theoretical ecology, but no one since has touched it," Allesina said. "Everybody cited it, and kind of disproved it metaphorically, but it's nice to go back to the original formulation and extend it."

###

University of Chicago Medical Center: http://www.uchospitals.edu

Thanks to University of Chicago Medical Center for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 14 time(s).

Source: http://www.labspaces.net/117728/A_classic_model_for_ecological_stability_revised_____years_later

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Stars mourn Whitney Houston at rousing New Jersey funeral (Reuters)

[unable to retrieve full-text content]Reuters - Stars, family and friends mourned Whitney Houston in a spirited Baptist funeral service at her hometown church on Saturday, a week after the death of the singer whose spectacular voice made her one of the biggest pop stars of her era.

Source: http://us.rd.yahoo.com/dailynews/rss/music/*http%3A//news.yahoo.com/s/nm/20120218/music_nm/us_whitneyhouston

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Sunday, February 19, 2012

Obama: Manufacturing rebounding after painful time

President Barack Obama greets the crowd after a tour of the Boeing 787 factory on Friday, Feb. 17, 2012, in Everett, Wash. (AP Photo/The Seattle Times, Mike Siegel, Pool)

President Barack Obama greets the crowd after a tour of the Boeing 787 factory on Friday, Feb. 17, 2012, in Everett, Wash. (AP Photo/The Seattle Times, Mike Siegel, Pool)

President Barack Obama checks out the overhead storage compartments while touring a Boeing 787 during a tour of the Boeing 787 factory on Friday, Feb. 17, 2012 in Everett, Wash. (AP Photo/The Seattle Times, Mike Siegel, Pool)

President Barack Obama greets school children from Medina Elementary School in Medina, Wash., Friday, Feb. 17, 2012. Obama, who attended a fundraiser nearby, is on a three-day trip to the West Coast. (AP Photo/Susan Walsh)

(AP) ? President Barack Obama says the painful restructuring of America's manufacturing base means a lot of jobs are gone forever, but that does not mean Americans must "settle for a lesser future."

In his weekly radio and Internet address Saturday, Obama said American manufacturers are reinventing themselves with new technology and new efficiencies that have helped lead to what the administration claims are 3.7 million new jobs created over the past two years.

"Factories where people thought they'd retire have left town. Jobs that provided a decent living have been shipped overseas" and will not return, Obama said. "But that doesn't mean we have to settle for a lesser future."

He recorded the address while visiting a massive Boeing Co. manufacturing plant near Seattle on Friday. He toured a modern factory floor and the inside of one of the aircraft maker's new flagship Dreamliner passenger jets.

"Companies like Boeing are realizing that even when we can't make things cheaper than China, we can make things better," Obama said in the weekly address. "That's how we're going to compete globally."

Delivering the Republican address, Washington Rep. Cathy McMorris Rodgers accused Obama of overspending that will set the country up for a financial implosion like the one in Greece.

"Instead of leading the effort to bring down our debt and make tough choices, the president is proposing that we spend more and more," she said.

While at Boeing on Friday, Obama announced steps to offer financing to U.S. companies to match help their foreign competitors get, with the goal of helping American industries compete.

Obama called on Congress to extend the Export-Import Bank's authorization. White House officials said the bank will reach its lending limit at the end of March and Obama pointed to it as a key player in helping promote U.S. exports.

At the same time, the White House announced that Boeing will participate in an Export-Import Bank program that helps companies advance money to suppliers on export-related contracts. Administration officials said Boeing would be committing to more than $700 million in short-term credit this year. Officials said the arrangement would help Boeing compete for foreign clients against European jet maker Airbus.

Facing re-election, Obama has pointed to a decline in unemployment and trumpeted a recent boost in manufacturing jobs as an indicator of an economy on the mend. Republicans seeking the White House have accused Obama of failing to steer the economy out of a deep recession.

____

Obama address: www.whitehouse.gov

GOP address: http://www.youtube.com/HouseConference

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-02-18-Obama/id-2699f70b30eb49b79004ae303380226f

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'Angry Birds' will be flying with zero gravity next month

Rovio

By Matthew Hawkins

The latest "Angry Birds" spin-off has been announced. This time, Rovio is taking the war into the stars above. Arriving on March 22 is the aptly titled "Angry Birds Space."

As the publisher states: "Angry Birds Space is a completely new game with innovative new gameplay, but with some of the familiar Angry Birds elements that fans already know and love -- plus some surprises!"

The announcement also has the following teaser trailer:

Rovio states that more details will be revealed in early March, before the final product lands. The official site is a good place to keep bookmarked for all "Angry Bird" diehards for wish to be in the loop.

As for where it'll be landing, the answer appears to be everywhere: "on March 22nd we will launch simultaneously in mobile gaming, animation, retail, and publishing. Not only is this a first for us as an integrated entertainment company, but the first time this has ever been done for a mobile game!"

Versions for smartphones are a no-brainer, it's the words "animation" and "publishing" that stick out the most. Will we be treated to a line of tie-in cartoons and comic books? Given all the "Angry Birds" merchandise that is already on the store shelves, it's a safe bet.

Related stories:

Matthew Hawkins is an NYC-based game journalist who has also written for EGM, GameSetWatch, Gamasutra, Giant Robot, and numerous others. He also self-publishes his own game culture zine, is part of Attract Mode, and co-hosts The Fangamer Podcast. You can keep tabs on him via?Twitter,?or his personal home-base,?FORT90.com.

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Source: http://ingame.msnbc.msn.com/_news/2012/02/17/10437046-angry-birds-will-be-flying-with-zero-gravity-next-month

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Saturday, February 18, 2012

Bookkeeping New York Outsourcing tools can rate of growth your ...

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Source: http://www.usedcars-sacramentoca.com/2012/02/18/bookkeeping-new-york-outsourcing-tools-can-rate-of-growth-your-business/

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Microchip Implant Gives Medication On Command

News | Health

A tiny chip implanted under the skin can dole out dozens of doses of osteoporosis medication right on schedule


microchip for medication deliveryChipping away at drug delivery: With a tiny implanted chip, filled with individual doses of medication, a patient might soon be able to forget all about daily shots--and perhaps even pills. Image: MicroCHIPS, Inc., Massachusetts

For people who face frequent needle jabs to treat chronic conditions, a new technology is on the horizon that might make treatment a lot less painful.

Researchers report that a new wirelessly controlled microchip, implanted under the skin, can safely and reliably give osteoporosis patients the daily dose of a drug that they need for at least 20 days in a row. The findings were presented at the American Association for the Advancement of Science annual meeting in Vancouver and published online Thursday in Science Translational Medicine.

Some 55,000 people in the U.S. with osteoporosis face daily injections of a bone-boosting hormone (known as human parathyroid hormone fragment, which is the basis for the drug teriparatide, sold as Forteo). But during a two-year daily regimen of the shots, close to three quarters of osteoporosis patients fail to take the drug as often as they are supposed to. High noncompliance makes this condition an especially compelling target for an automatic drug-dosing system.

"In a silent disease like osteoporosis, [patients] don't feel any difference, and they just give up the injections all together," says Robert Farra, co-author of the study and chief operating officer at MicroCHIPS, the company that makes the chip. Doctors can either preprogram the new device for a release schedule or send release instructions directly to it via a dedicated radio frequency.

For the study, eight postmenopausal women with osteoporosis had the chip?which is about three by five centimeters and can be implanted during an office visit?inserted under the skin around their bellies for about three and a half months. Daily doses of teriparatide were preprogrammed to release for about 20 days during the middle of the trial. Seven of the eight received most of their doses right on schedule, and each of these said they would opt in for another chip?most reported that they had forgotten that it was there.

Microchips like these could also be used for other conditions that demand discrete drug dosing, such as multiple sclerosis, for which some patients must inject a dose of interferon once every two days. Therapies that use hormones are particularly appealing for adaptation to microchip delivery because the body usually releases hormones intermittently?just as the chip does, Farra says. In the future, a device like this might also be able to help diabetics both monitor and treat their condition.

This sort of direct communication in an implanted device could help patients stick to medication regimes without having to face a syringe or pill bottle.

Remote controlled
The device can be preprogrammed or controlled wirelessly via the Medical Implant Communication Services (MICS) band, set aside for the U.S. Food and Drug Administration (FDA) by the Federal Communications Commission. And the device can also report back dose-delivery data to a computer-based system.

Scientists demonstrated that this sort of wirelessly controlled drug delivery might be possible in 1999. Some major technological hurdles needed to be cleared in the interim, Farra says.

The first challenge was figuring out how to create seals on the drug-holding wells that would stand up to moisture inside the body. Researchers solved this by using compression welding to create a hermetic seal around the well's metallic membrane. The second hurdle was figuring out how best to open those tight seals. The scientists settled on an electrical current that would melt the membrane on command. The final hurdle involved scaling things down?getting all the components and wells onto a chip that would fit comfortably under the skin.

Source: http://rss.sciam.com/click.phdo?i=bda756fd28cd45364acf79ae79318bad

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